Prevention and early diagnosis are the best and most effective ways for defeating HIV.
There is still no vaccine, but treatments with antiretroviral drugs are now available which,
in many cases, allow the infection to become chronic. However, research has highlighted
side effects of these drugs and the fact that a flare-up of the infection occurs if the therapy
is stopped. In recent years, the presence of virus reserves located in various parts of the
body, including the brain, has been hypothesized. The possibility of controlling the
infection of healthy cells and of interrupting the proliferation of virions inside the brain has
been studied, proposing optimal control strategies.
Dettaglio pubblicazione
2023, INFECTIOUS DISEASE MODELLING, Pages 10-26 (volume: 9)
Optimal therapy for HIV infection containment and virions inhibition (01a Articolo in rivista)
DI GIAMBERARDINO Paolo, Iacoviello Daniela, Zubair Muhammad
keywords