In the last decades several epidemic emergencies have been affecting the world, influ encing the social relationships, the economics and the habits. In particular, starting in the
early 0
80, the Acquired Immunodeficiency Syndrome, AIDS, is representing one of the most
worrying sanitary emergency, that has caused up to now more than 25 million of dead
patients. The infection is caused by the Human Immunodeficiency Virus, HIV, that may be
transmitted by body fluids; therefore with wise behaviours the epidemic spread could
rapidly be contained. This sanitary emergency is peculiar for the long incubation time: it
can reach even 10 years, a long period in which the individual can unconsciously infect
other subjects. The identification of the number of infected unaware people, mandatory to
define suitable containment measures, is here obtained by using the extended Kalman
filter applied to a noisy model in which, reasonably, only the number of infected diagnosed
patients is available. Numerical simulations and real data analysis support the effective ness of the approach
Dettaglio pubblicazione
2023, INFECTIOUS DISEASE MODELLING, Pages 341-355 (volume: 8)
Early estimation of the number of hidden HIV infected subjects: An extended Kalman filter approach (01a Articolo in rivista)
DI GIAMBERARDINO Paolo, Iacoviello Daniela
Gruppo di ricerca: Nonlinear Systems and Control
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